Triazolyl-substituted pyridyl compounds useful as kinase inhibitors

US8987311B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Dharmpal S. Dodd · Princeton, US
• Christopher P. Mussari · Princeton, US
• Rajeev S. Bhide · Princeton Junction, US
• Satheesh Kesavan Nair · Kanchinakote, IN
• Venkatram Reddy Paidi · Bengaluru, IN
• Sreekantha Ratna Kumar · Bengaluru, IN
• Abhisek Banerjee · Narayanpur, IN
• Ramesh Kumar Sistla · Bengaluru, IN
• William J. Pitts · Newtown, US
• John Hynes · Washington Crossing, US

Key dates

• Filing date: Jan 11, 2013
• Grant date: Mar 24, 2015
• Expiry date: Jan 11, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the following formula: (I) wherein: A is an optionally substituted triazole, or a stereoisomer or a pharmaceutically-acceptable salt thereof, are useful as kinase modulators, including IRAK-4 modulation.