Patent · US Active

Lisofylline analogs and methods for use

US8987321B2 · kind B2 · utility

0Cited by

10References

12Claims

0Family size

Assignee

University of Virginia Patent Foundation · US

Inventors

Timothy L. Macdonald · Charlottesville, US
Jerry L. Nadler · Charlottesville, US
Peng Cui · Suwon-si, KR

Key dates

Filing date	Jun 27, 2013
Grant date	Mar 24, 2015
Priority date	—
Expiry date	Jun 27, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides analogs of a Lysofylline (LSF), and synthetic methods for the preparation of such analogs. The have the active side chain moiety (5-R-hydroxyhexyl) of LSF and can have greater potency and oral bioavailability than LSF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.