Patent · US Active

Process of separating chiral isomers of chroman compounds and their derivatives and precursors

US8987480B2 · kind B2 · utility

0Cited by

2References

26Claims

0Family size

Assignee

DSM IP ASSETS B.V. · NL

Inventors

Gerhard Schiefer · Basel, CH
Thomas Netscher · Bad Krozingen, DE
Alexander Lucia Leonardus Duchateau · Echt, NL

Key dates

Filing date	May 8, 2012
Grant date	Mar 24, 2015
Priority date	—
Expiry date	May 8, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D311/72
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process of separating chiral isomers of chroman compounds, particularly tocopherols and tocotrienols as well as the esters and intermediates thereof. It has been found that this process allows a separation of the desired isomer with a higher yield and enables the use of the non-desired isomers in a very efficient way. Said process is particularly useful when implemented in an industrial process. Furthermore, it has been found that this process allows using isomer mixtures as they result from traditional industrial synthesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.