Enantiomerically pure amines

US8987498B2 · kind B2 · utility

Assignee

• NABRIVA THERAPEUTICS GMBH · AT

Inventors

• Rosemarie Riedl · Wien, AT
• Werner Heilmayer · Staprijk, AT
• Lee Spence · Wien, AT
• Atchyuta Rama Chandra Murty Bulusu · Perchtoldsdorf, AT

Key dates

• Filing date: May 23, 2011
• Grant date: Mar 24, 2015
• Expiry date: May 23, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of formulawherein PROT is an amine protecting group and PROT′ is hydrogen; or PROT and PROT′ together with the nitrogen atom to which they are attached form a heterocyclic ring as an amine protecting group, and PROT″ is a thiol protecting group, processes for its production, intermediates in their production and production of intermediates in stereoisomerically pure form, and their use for the production of pharmaceutically active compounds.