Method for counteracting the perception of sweat malodour by decreasing the function of carboxylic acid-binding olfactory receptors
US8993526B2 · kind B2 · utility
1Cited by
1References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 12, 2013 |
| Grant date | Mar 31, 2015 |
| Priority date | — |
| Expiry date | Jun 12, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to the identification of carboxylic acids, present in human sweat, as natural ligands of a specific subgroup of seven olfactory receptor (OR) belonging to class 1 within the OR classification. The invention encompasses the use of the interaction of OR polypeptides and carboxylic acids as the basis of screening assays for agents that specifically modulate the activity of the seven ORs of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.