Patent · US Active

Stereoselective synthesis of bicyclic heterocycles

US8993753B2 · kind B2 · utility

0Cited by

6References

1Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Markus Ostermeier · Biberach an der Riß, DE
Juergen Daeubler · Biberach an der Riß, DE
Guenther Huchler · Biberach an der Riß, DE
Stephan Kling · Warthausen, DE
Marco Santagostino · Magenta, IT

Key dates

Filing date	Jan 14, 2014
Grant date	Mar 31, 2015
Priority date	—
Expiry date	Jan 14, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a process for the stereoselective preparation of compounds of formulae (1A) and (1B)and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.