Fluorescent boron-substituted dipyrromethenes and use thereof for diagnosis
US8993781B2 · kind B2 · utility
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1References
12Claims
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Key dates
| Filing date | Dec 28, 2009 |
| Grant date | Mar 31, 2015 |
| Priority date | — |
| Expiry date | Jan 28, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel fluorescent compounds derived from non-fluorinated dipyrromethene-boron, to a method for preparing same and to the use thereof for the fluorescent marking of biological molecules. The invention also relates to biological molecules marked with said fluorescent compounds, and to the use thereof in detection methods such as medical diagnosis methods. More particularly, the detection methods of the invention are particularly useful for diagnosing neurodegenerative diseases such as Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.