Highly active multidentate catalysts for efficient alkyne metathesis

US8993804B2 · kind B2 · utility

Assignee

• The Regents of the University of Colorado, a Body Corporate · US

Inventors

• Wei Zhang · Brecksville, US
• Jyothish Kuthanapillil · Boulder, US
• Qi Wang · Singapore, SG

Key dates

• Filing date: Mar 8, 2013
• Grant date: Mar 31, 2015
• Expiry date: Apr 20, 2033

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2540/62
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to highly active and selective catalysts for alkyne metathesis. In one aspect, the invention includes a multidentate organic ligand wherein one substrate-binding site of the metal center is blocked. In another aspect, the invention includes N-quaternized or silane-based multidentate organic ligands, capable of binding to metals. In yet another aspect, the invention includes N-quaternized or silane-based multidentate catalysts. The catalysts of the invention show high robustness, strong resistance to small alkyne polymerization and significantly enhanced catalytic activity compared to their corresponding non-quaternized or non-silane-based multidentate catalyst analogs.