Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US8996116B2 · kind B2 · utility
60Cited by
240References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 1, 2010 |
| Grant date | Mar 31, 2015 |
| Priority date | — |
| Expiry date | Jan 26, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/36071
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and devices for the treatment of chronic pain by modulation of the cholinergic anti-inflammatory pathway. In particular, the methods and systems described herein may be used to enhance chronic pain therapies such as spinal cord stimulation (SCS). Thus, the present invention describes devices and methods for modulation of the cytokine pathway by stimulation of the neuronal cholinergic anti-inflammatory pathway (NCAP) to enhance the treatment of chronic pain by SCS. The use of NCAP in conjunction with SCS may potentiate the effects of SCS and/or prevent the desensitization of the patient to SCS.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.