Patent · US Active

Using oligonucleotide microarrays to analyze genomic differences for the prediction of heterosis

US8996318B2 · kind B2 · utility

3Cited by

2References

3Claims

0Family size

Assignees

PIONEER HI-BRED INTERNATIONAL, INC. · US
E.I. DU PONT DE NEMOURS AND COMPANY · US

Inventors

Mary Beatty · Earlham, US
James Janni · Johnston, US
Jonathan Lightner · Johnston, US
J. Antoni Rafalski · Wilmington, US

Key dates

Filing date	Dec 29, 2008
Grant date	Mar 31, 2015
Priority date	—
Expiry date	Mar 9, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/16
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A novel method for prediction of the degree of heterotic phenotypes in plants is disclosed. Structural variation analyzes of the genome are used to predict the degree of a heterotic phenotype in plants. In some examples, copy number variation is used to predict the degree of heterotic phenotype. In some methods copy number variation is detected using competitive genomic hybridization arrays. Further, methods for optimizing the arrays are disclosed, together with kits for producing such arrays, as well as hybrid plants selected for development based on the predicted results.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.