Patent · US Active

Compositions of GnRH related compounds and processes of preparation

US8999383B2 · kind B2 · utility

2Cited by
81References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 7, 2009
Grant dateApr 7, 2015
Priority date
Expiry dateNov 6, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K7/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compositions of GnRH related compounds that are suitable for oral administration, injectable administration and other forms of administration wherein the gelling characteristics of the composition are a factor. The compositions of the present invention comprise a therapeutically effective amount of one or more GnRH related compound, and a sufficient amount of at least one anti-gelling agents to reduce the gelation of the GnRH related compound. The present invention also provides processes for preparation of a composition of one or more GnRH related compound, wherein the process comprises mixing the GnRH related compound with one or more anti-gelling agents, wherein the anti-gelling agent comprises a medium chain fatty acid salt, or an ester, an ether, or a derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms or is a surface active agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.