Glucose dehydrogenase
US8999691B2 · kind B2 · utility
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4References
11Claims
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Key dates
| Filing date | Jun 29, 2011 |
| Grant date | Apr 7, 2015 |
| Priority date | — |
| Expiry date | Oct 28, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a modified glucose dehydrogenases that has dramatically increased productivity in Escherichia coli and dramatically increased thermal stability, which is obtained by introducing specific amino acid mutations to glucose dehydrogenase derived from Botryotinia fuckeliana. Also disclosed is a modified glucose dehydrogenases that has dramatically increased productivity in E. coli and dramatically increased thermal stability, which is obtained by replacing two amino acid residues in glucose dehydrogenase of fungal origin with cysteine residues. The novel glucose dehydrogenase has a low reactivity to xylose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.