Patent · US Active

Polyol modified aminoglycoside-lipid conjugates

US8999942B2 · kind B2 · utility

0Cited by

1References

11Claims

0Family size

Assignee

University of Manitoba · CA

Inventors

Frank Schweizer · Winnipeg, CA
Smritilekha Bera · Kohima, IN
George Zhanel · Winnipeg, CA

Key dates

Filing date	Apr 5, 2011
Grant date	Apr 7, 2015
Priority date	—
Expiry date	Apr 5, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H17/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

In some aspects, the present invention provides aminoglycoside derivatives thereof that exhibit antibacterial activity. In some aspects, the aminoglycoside derivatives comprise compounds consisting of (a) an ammoglycoside group and (b) at least one hydrophobic carbamate and alkoxy group to the primary or secondary hydroxy position of the aminolvcoside group and salts thereof. Additionally, methods of treating and preventing bacterial infections using the aminoglycoside derivatives are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.