Patent · US Active

Compound useful for the treatment of degenerative and inflammatory diseases

US8999979B2 · kind B2 · utility

7Cited by

2References

13Claims

0Family size

Assignee

Galapagos NV · BE

Inventors

Christel Jeanne Marie Menet · Mechelen, BE
Koen Kurt Smits · Mechelen, BE

Key dates

Filing date	Sep 13, 2013
Grant date	Apr 7, 2015
Priority date	—
Expiry date	Sep 13, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A novel compound able to inhibit JAK is disclosed, that is according to Formula I:or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.