Methods and devices for providing prolonged drug therapy

US9000038B2 · kind B2 · utility

Assignee

• ALZA CORPORATION · US

Inventors

• Andrew Lam · South San Francisco, US
• Padmaja Shivanand · Mountain View, US
• Atul D. Ayer · Palo Alto, US
• Zahedeh Hatamkhany · San Jose, US
• Richard G. Weyers · Los Altos, US
• Suneel Gupta · Sunnyvale, US
• Diane R. Guinta · Palo Alto, US
• Carol A. Christopher · Belmont, US
• Samuel R. Saks · Palo Alto, US
• Lawrence G. Hamel · Palo Alto, US
• Jeri D. Wright · Dublin, US

Key dates

• Filing date: Mar 13, 2013
• Grant date: Apr 7, 2015
• Expiry date: Mar 13, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/4458
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.