Patent · US Active

Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors

US9000172B2 · kind B2 · utility

5Cited by
2References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 12, 2012
Grant dateApr 7, 2015
Priority date
Expiry dateOct 12, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.