Process for preparing lipid nanoparticles
US9005666B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 11, 2008 |
| Grant date | Apr 14, 2015 |
| Priority date | — |
| Expiry date | Jan 9, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for preparing nanocapsules with a liquid lipid core and a solid lipid shell, charged with at least one active agent. The process contains at least the steps of formulating a microemulsion by phase inversion of an emulsion, totally or partially forming from at least one active agent a second composition different than the microemulsion, placing the microemulsion in contact with the second composition under conditions suitable for interaction of the active agent with the microemulsion, and chill-hardening the microemulsion that has interacted with the active agent, to obtain the nanocapsules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.