Patent · US Active

Targeted genomic modification with partially single-stranded donor molecules

US9005973B2 · kind B2 · utility

59Cited by

28References

7Claims

0Family size

Assignee

Sangamo Biosciences, Inc. · US

Inventors

Gregory J. Cost · Berkeley, US
Dmitry Guschin · Richmond, US
Fyodor Urnov · Richmond, US

Key dates

Filing date	Jul 8, 2011
Grant date	Apr 14, 2015
Priority date	—
Expiry date	Jul 8, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/81
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.