Method for selecting clone of induced pluripotent stem cells
US9005975B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | May 28, 2010 |
| Grant date | Apr 14, 2015 |
| Priority date | — |
| Expiry date | Mar 10, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
To efficiently identify and select a clone from clones of induced pluripotent stem cells (iPS cell) having low tumor formation rate in vivo when allowed to differentiate and transplanted in a living body, iPS cells of the clones are induced to differentiate, undifferentiated cells among the cells after the induction of differentiation are detected, and a clone having the content of the undifferentiated cell below a control is selected.
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