Optical reporter compositions
US9005985B2 · kind B2 · utility
0Cited by
33References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2013 |
| Grant date | Apr 14, 2015 |
| Priority date | — |
| Expiry date | Feb 7, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particles of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.