Dihydropteridinones I

US9006226B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Kai Gerlach · Biberach, DE
• Christian Eickmeier · Mittelbiberach, DE
• Claudia Heine · Biberach, DE
• Niklas Heine · Eberhardzell, DE
• Alexander Weber · Biberach an der Riß, DE

Key dates

• Filing date: Feb 14, 2013
• Grant date: Apr 14, 2015
• Expiry date: Mar 1, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to dihydropteridinones, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Aβ peptides.