Camptothecin derivatives having anti-tumor activity
US9006439B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Apr 6, 2012 |
| Grant date | Apr 14, 2015 |
| Priority date | — |
| Expiry date | Apr 6, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel camptothecin derivatives having anti-tumor activity (the basic structure thereof is as shown in the figure) and compositions of such compounds and use thereof. The compounds according to the present invention exhibit very good water solubility and stability, show good selectivity among drugs of the same category, and have a very high therapeutic index. Such compounds are promising as therapeutic agents for treating tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.