Broad spectrum vaccine against typhoidal and non-typhoidal Salmonella disease
US9011871B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 2012 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Nov 6, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is drawn to multivalent Salmonella enterica serovar conjugate vaccines comprising conjugates of S. Typhimurium, S. Enteritidis, S. Choleraesuis, S. Typhi, S. Paratyphi A and optionally S. Paratyphi B, wherein the conjugates comprise a hapten antigen and a carrier antigen, wherein at least one of the hapten antigens or carrier antigens is characteristic of the Salmonella enterica serovar. The present invention also provides Salmonella enterica serovar reagent strains to produce the multivalent conjugate vaccines and attenuated Salmonella enterica serovars for use as vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.