Patent · US Active

Bioluminescent assays utilising secreted luciferases

US9012164B2 · kind B2 · utility

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5References

19Claims

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Inventors

Marco Peter Leu · Perth, AU
John Michael Daly · Perth, AU

Key dates

Filing date	Mar 12, 2013
Grant date	Apr 21, 2015
Priority date	—
Expiry date	Mar 12, 2033

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/182
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are methods for determining the amount or activity of one or more luciferases and methods for measuring the luminescent signal generated by one or more luciferases in a sample, the methods comprising incubating the sample with a reactive substrate(s) of the luciferase(s) to be analyzed and a reducing agent to inactivate a first luciferase, wherein the first luciferase, in its native form, is a secreted luciferase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.