Recombinant carrier molecule for expression, delivery and purification of target polypeptides
US9012199B2 · kind B2 · utility
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Key dates
| Filing date | Oct 23, 2013 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Oct 23, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/35
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B (Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.