Patent · US Active

Method for producing platelets from megakaryocytes

US9012221B2 · kind B2 · utility

11Cited by

1References

5Claims

0Family size

Assignees

INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) · FR
UNIVERSITE DE PARIS DESCARTES · FR
ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR
Universite de Versailles Saint-Quentin-en-Yvelines · FR

Inventors

Dominique Baruch · Paris, FR
Elisabeth Cramer-Borde · Boulogne, FR
Claire Dunois · Paris, FR

Key dates

Filing date	Dec 4, 2009
Grant date	Apr 21, 2015
Priority date	—
Expiry date	Aug 19, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a method for producing platelets from mature megakaryocytes. More particularly, the invention relates to an ex vivo method for producing platelets, from mature megakaryocytes, said method comprising a step of subjecting a suspension of mature megakaryocytes to a flow having a minimal shear rate of 600 s−1 on a solid phase coated with Von Willebrand factor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.