ω-Aminocarboxylic acids, ω-aminocarboxylic acid esters, or recombinant cells which produce lactams thereof

US9012227B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Andreas Karau · Hamburg, DE
• Volker Sieber · Dresden, DE
• Thomas Haas · Munster, DE
• Harald Haeger · Thedinghausen, DE
• Katrin Grammann · Johannesweg, DE
• Bruno Buehler · Dortmund, DE
• Lars Blank · Dortmund, DE
• Andreas Schmid · Berkeley, US
• Guido Jach · Neunburg vorm Wald, DE
• Bernd Lalla · Cologne, DE
• Andreas Mueller · Leverkusen, DE
• Katrin Schullehner · Cologne, DE
• Peter Welters · Nettetal, DE
• Thorsten Eggert · Hattingen, DE
• Andrea Weckbecker · Cologne, DE

Key dates

• Filing date: Dec 12, 2008
• Grant date: Apr 21, 2015
• Expiry date: Jan 16, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/005
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ω-aminocarboxylic acids, more ω-aminocarboxylic acid esters or more lactams derived from ω-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ω-aminocarboxylic acids, of ω-aminocarboxylic acid esters or of lactams derived from ω-aminocarboxylic acids, the ω-aminocarboxylic acids, ω-aminocarboxylic acid esters or lactams derived from ω-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ω-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.