Rapid detection and identification of energetic materials with surface enhanced raman spectrometry (SERS)
US9012241B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 27, 2010 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Jan 4, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/18
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, wherein the plurality of organic molecules preferentially interact with one or more analytes when placed in proximity therewith. According to another embodiment, a method for detecting analytes includes contacting a fluid having one or more analytes of interest therein with a plurality of metal nanoparticles, each metal nanoparticle having a plurality of organic molecules tethered thereto, and detecting Raman scattering from an analyte of interest from the fluid, the analyte interacting with one or more of the plurality of organic molecules. In another embodiment, a method includes chemically modifying a plurality of cyclodextrin molecules at a primary hydroxyl moiety to create a chemical handle, and tethering the plurality of cyclodextrin molecules to a metal nanoparticle using the chemical handle. Other systems and methods for detecting analytes are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.