Aptamer for chymase, and use thereof
US9012420B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Jun 11, 2010 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | May 3, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/322
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are an aptamer bound to chymase to inhibit activity of chymase; an aptamer containing a nucleotide sequence represented by X1GAUAGAN1N2UAAX2 wherein X1 and X2 are the same or different and each is A or G, and N1 and N2 are the same or different and each is A, G, C, U or T; a complex containing the aptamer and a functional substance (e.g., affinity substance, labeling substance, enzyme, drug delivery medium, drug and the like); a pharmaceutical or a reagent containing the aptamer or complex; a detection and a purification methods of chymase using the aptamer or complex and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.