Dual-acting imidazole antihypertensive agents
US9012485B2 · kind B2 · utility
2Cited by
36References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 9, 2014 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Jan 9, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to compounds having the formula:wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.