Cyclohexyl carbamate compounds as active anti-cellulite ingredients

US9012497B2 · kind B2 · utility

Assignee

• SYMRISE AG · DE

Inventors

• Imke Meyer · Bodenwerder, DE
• Heiko Oertling · Lausanne, CH
• Nadine Hillebrand · Steinheim, DE
• Claudia Gömann · Warbsen, DE
• Rahim Brodhage · Rinteln, DE

Key dates

• Filing date: May 25, 2010
• Grant date: Apr 21, 2015
• Expiry date: May 25, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I)wherein A denoteswherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl,wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms,B denotes NR1R2, whereinR1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms,R2 denotes an organic radical having 1 to 14 carbon atoms, andwherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 memb…