Patent · US Active

DNA constructs for specific inhibition of gene expression by RNA interference

US9012620B2 · kind B2 · utility

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0References

8Claims

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Assignee

Mologen AG · DE

Inventors

Matthias Schroff · Berlin, DE
Detlef Oswald · Berlin, DE

Key dates

Filing date	Nov 22, 2006
Grant date	Apr 21, 2015
Priority date	—
Expiry date	Jul 7, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2330/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to expression constructs for targeted inhibition of gene expression and methods for their production and which, after transfection thereof into eukaryotic cells, are suitable for inhibiting in a targeted manner these cells formation of defined proteins by RNA interference, wherein the method is a three step method requiring no PCR steps and is carried out in one reaction vessel in a few hours and are suitable for multiple gene expression inhibition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.