Compositions and methods using siRNA molecules and siRNA cocktails for the treatment of breast cancer
US9012622B2 · kind B2 · utility
3Cited by
0References
12Claims
0Family size
Inventors
Key dates
| Filing date | Dec 31, 2009 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Jan 18, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides small interfering RNA (siRNA) molecules, compositions containing the molecules, and methods of using the molecules and compositions to treat breast cancer. In one aspect, a multi-targeted siRNAi cocktail is disclosed. The siRNA molecules may be encapsulated in nanoparticles to further enhance their anti-cancer activity. The compositions may also be used in combination with other anti-cancer agents, such as bevacizumab.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.