Method for producing 30-halogenated betulinic acid
US9012666B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Mar 15, 2012 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Mar 15, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J63/008
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention discloses a method for producing 30-halogenated betulinic acid. Betulin is used as a raw material and selectively oxidized and halogenated to generate 30-betulinic acid, and the selected oxidation and halogenation agent has high selectivity and does not affect C-3 hydroxyl or carbon-carbon double bonds. Oxidation and halogenation are completed in one step, so the process route is short, the treatment method is simple, and the product is purified easily.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.