Flow cytometer apparatus for three dimensional difraction imaging and related methods
US9013692B2 · kind B2 · utility
16Cited by
10References
37Claims
0Family size
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Key dates
| Filing date | Jun 11, 2009 |
| Grant date | Apr 21, 2015 |
| Priority date | — |
| Expiry date | Aug 18, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1497
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow cytometer assembly includes a fluid controller configured to form a hydrodynamically focused flow stream including an outer sheath fluid and an inner core fluid. A coherent light source is configured to illuminate a particle in the inner core fluid. A detector is configured to detect a spatially coherent distribution of elastically scattered light from the particle excited by the coherent light source. An analyzing module configured to extract a three-dimensional morphology parameter of the particle from a spatially coherent distribution of the elastically scattered light.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.