5.9 kDa peptide immunoassay method
US9017959B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Oct 13, 2010 |
| Grant date | Apr 28, 2015 |
| Priority date | — |
| Expiry date | Oct 13, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/08
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is an immunoassay method whereby a 5.9 kDa peptide which results from the degradation of the α-E chain and α chain of human fibrinogens and which is used as a peptide marker for diagnosing hepatic disease can be specifically assayed in a biological sample containing contaminating peptides by bringing antibodies that recognize the N terminal of said peptide marker and antibodies that recognize the C terminal of said peptide marker into contact with said peptide marker, forming immune complexes of said peptide marker and the two antibodies, and immunoassaying the obtained immune complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.