Patent · US Active

Sugar-chain modified yeast and method for producing glycoprotein using the same

US9017969B2 · kind B2 · utility

0Cited by

1References

15Claims

0Family size

Assignee

National Institute of Advanced Industrial Science and Technology · JP

Inventors

Hiroko Abe · Takamatsu, JP
Kazuya Tomimoto · Samukawa, JP
Yasuko Fujita · Samukawa, JP
Tomoko Iwaki · Samukawa, JP
Yasunori Chiba · Tsukuba, JP
Yoshihiro Nakajima · Osaka, JP
Kenichi Nakayama · Takamatsu, JP
Masatoshi Kataoka · Takamatsu, JP
Shouki Yatsushiro · Takamatsu, JP
Shohei Yamamura · Takamatsu, JP

Key dates

Filing date	Mar 1, 2012
Grant date	Apr 28, 2015
Priority date	—
Expiry date	Oct 25, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y302/01003
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.