Patent · US Active

Non-wild-type organophosphorus acid anhydrolases for enzymatic decontamination

US9017982B1 · kind B1 · utility

2Cited by

0References

4Claims

0Family size

Assignee

The United States of America as represented by the Secretary of the Army · US

Inventors

Saumil S. Shah · Columbia, US
Mark A. Guelta · White Marsh, US
Steven P. Harvey · Timonium, US

Key dates

Filing date	Dec 17, 2013
Grant date	Apr 28, 2015
Priority date	—
Expiry date	Dec 17, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y301/08002
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are non-wild-type organophosphorus acid anhydrolases that are capable of degrading (ethyl {2-[bis(propan-2-yl)amino]ethyl}sulfanyl) (methyl)phosphinate and other V-agents. Particular embodiments include an organophosphorus acid anhydrolase including an amino acid substitution at position 212.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.