Protease resistant insulin analogues
US9018161B2 · kind B2 · utility
9Cited by
27References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 2007 |
| Grant date | Apr 28, 2015 |
| Priority date | — |
| Expiry date | Jul 15, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.