SGLT inhibitors

US9018249B2 · kind B2 · utility

Assignee

• PANACEA BIOTEC LIMITED · IN

Inventors

• Rajesh Jain · New Delhi, IN
• Sanjay Trehan · Hyderabad, IN
• Jagattaran Das · New Delhi, IN
• Gurmeet Kaur Nanda · New Delhi, IN
• Sastry V. R. S. Thungathurthi · New Delhi, IN
• Nishan Singh · New Delhi, IN
• Sudhir Kumar Sharma · New Delhi, IN

Key dates

• Filing date: Sep 12, 2012
• Grant date: Apr 28, 2015
• Expiry date: Sep 12, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H7/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula I and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2).