Transgenic pig in which HO-1 and TNFR1-Fc are simultaneously expressed, and method for producing same
US9018439B2 · kind B2 · utility
1Cited by
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17Claims
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Key dates
| Filing date | Dec 21, 2010 |
| Grant date | Apr 28, 2015 |
| Priority date | — |
| Expiry date | Aug 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fe fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is produced by the method, and in which immune rejection response is inhibited. The present invention also relates to a somatic-cell-donating cell strain for producing the transgenic pig, and to a method for producing organs, from the transgenic pig, in which the immune rejection response is inhibited.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.