Method for detecting molecules through mass spectrometry
US9018580B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 15, 2010 |
| Grant date | Apr 28, 2015 |
| Priority date | — |
| Expiry date | Sep 15, 2030 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/427
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyzer, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyzer; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.