Patent · US Active

Treatment method using EGFR antibodies and SRC inhibitors and related formulations

US9023356B2 · kind B2 · utility

0Cited by
195References
14Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMar 14, 2008
Grant dateMay 5, 2015
Priority date
Expiry dateJun 14, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or modulation of cancer, particularly EGFR-mediated disease, with one or more EGFR modulator and src inhibitor in combination. The invention further relates to the treatment of cancer with anti-EGFR antibodies and src inhibitors. Methods and compositions for treatment of cancer with the antibody anti-EGFR mAb806 in combination or series with a src inhibitor or src inhibitors are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.