Patent · US Active

Microarray synthesis and assembly of gene-length polynucleotides

US9023601B2 · kind B2 · utility

78Cited by
107References
18Claims
0Family size

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Key dates

Filing dateSep 30, 2011
Grant dateMay 5, 2015
Priority date—
Expiry dateSep 30, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC40B40/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is disclosed a process for in vitro synthesis and assembly of long, gene-length polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in situ on a microarray platform. Specifically, there is disclosed a process for in situ synthesis of oligonucleotide fragments on a solid phase microarray platform and subsequent, “on device” assembly of larger polynucleotides composed of a plurality of shorter oligonucleotide fragments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.