Microvessels, microparticles, and methods of manufacturing and using the same

US9023638B2 · kind B2 · utility

Assignee

• Illumina, Inc. · US

Inventors

• John A. Moon · San Diego, US
• M. Shane Bowen · Encinitas, US
• Ryan C. Smith · Fremont, US
• Michel Perbost · Bethany, US
• Michal Lebl · Oro Valley, US
• Steven Modiano · San Diego, US

Key dates

• Filing date: Aug 16, 2013
• Grant date: May 5, 2015
• Expiry date: Aug 16, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N35/00732
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A plurality of isolated microvessels including a plurality of encoded microvessels each having a microbody and a reservoir core. The microbody is configured to separate a biological or chemical substance in the reservoir core from an ambient environment surrounding the microbody. The microbody includes a transparent material that at least partially surrounds the reservoir core and facilitates detection of an optical characteristic of the substance within the reservoir core. The microbody of each microvessel includes an identifiable code that distinguishes individual microvessels of the plurality of encoded microvessels from each other. The plurality of isolated microvessels also includes a plurality of compartments each configured to separate individual microvessels of the plurality of encoded microvessels from each other.