Triazolopyrazine derivatives

US9023851B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Lars Burgdorf · Frankfurt am Main, DE
• Melanie Schultz · Darmstadt, DE
• Carl Deutsch · Darmstadt, DE
• Horacio Comas · Centerville, US
• Dominique Swinnen · Braine-l'Alleud, BE
• Vincent Pomel · Annecy, FR
• Pascale Gaillard · Saint-Julien-en-Genevois, FR
• Brian L. Hodous · Cambridge, US

Key dates

• Filing date: Jul 29, 2011
• Grant date: May 5, 2015
• Expiry date: Jul 30, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula Iin which R1 and R2 have the meanings indicated in claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis.