Diarylacetylene hydrazide containing tyrosine kinase inhibitors

US9024021B2 · kind B2 · utility

Assignee

• SUN PHARMA ADVANCED RESEARCH COMPANY LTD. · IN

Inventors

• Prabal Sengupta · Salumbar, IN
• Hemant Ashvinbhai Chokshi · Salumbar, IN
• Chetan Surjitsingh Puri · Salumbar, IN
• Sabbirhusen Yusufbhai Chimanwala · Salumbar, IN
• Varun Anilkumar Mehta · Salumbar, IN
• Dipali Manubhai Desai · Salumbar, IN
• Trinadha Rao Chitturi · Salumbar, IN
• Rajamannar Thennati · Viralimalai, IN

Key dates

• Filing date: Jan 23, 2012
• Grant date: May 5, 2015
• Expiry date: Jan 23, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals.