Efficient process for the preparation of lapatinib and salts thereof by means of new intermediates
US9024023B2 · kind B2 · utility
1Cited by
1References
9Claims
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Key dates
| Filing date | Sep 3, 2013 |
| Grant date | May 5, 2015 |
| Priority date | — |
| Expiry date | Sep 3, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention refers to a new efficient process for the synthesis of the active pharmaceutical ingredient Lapatinib and salts thereof.In particular, the present synthesis is carried out employing new intermediates in which the amine function is protected by a group cleavable in basic milieu that provides a higher overall yield of the synthesis process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.