Stable anti-TNFR1 polypeptides, antibody variable domains and antagonists
US9028817B2 · kind B2 · utility
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Key dates
| Filing date | Oct 25, 2010 |
| Grant date | May 12, 2015 |
| Priority date | — |
| Expiry date | Oct 25, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to storage-stable anti-TNFR1 antibody single variable domains (dAbs), antagonists and multispecific ligands, as well as methods and uses of these. The anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands are useful for treating and/or preventing inflammatory disease, such as arthritis or COPD, as well as for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.