Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
US9028863B2 · kind B2 · utility
2Cited by
7References
14Claims
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Key dates
| Filing date | Apr 26, 2004 |
| Grant date | May 12, 2015 |
| Priority date | — |
| Expiry date | Aug 20, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.